Combination of Oncolytic Virotherapy with Different Antitumor Approaches against Glioblastoma

Combination of Oncolytic Virotherapy with Different Antitumor Approaches against Glioblastoma Full article

Journal

International Journal of Molecular Sciences
, E-ISSN: 1422-0067

Output data

Year: 2024, Volume: 25, Number: 4, Article number : 2042, Pages count : DOI: 10.3390/ijms25042042

Tags

glioblastoma; oncolytic viruses; chemotherapy; radiotherapy; immunotherapy; combination therapy

Authors

Ageenko Alisa ¹ , Vasileva Natalia ^1,2 , Richter Vladimir ¹ , Kuligina Elena ^1,2

Affiliations

1	Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Akad. Lavrentiev Ave. 8, 630090 Novosibirsk, Russia
2	LLC “Oncostar”, R&D Department, Ingenernaya Street 23, 630090 Novosibirsk, Russia

Funding (2)

1	МИНИСТЕРСТВО НАУКИ И ВЫСШЕГО ОБРАЗОВАНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ	ПФНИ РФ (2021-2030) 0245-2021-0005
2	Russian Science Foundation	РНФ №22-64-00041

Glioblastoma is one of the most malignant and aggressive tumors of the central nervous system. Despite the standard therapy consisting of maximal surgical resection and chemo- and radiotherapy, the median survival of patients with this diagnosis is about 15 months. Oncolytic virus therapy is one of the promising areas for the treatment of malignant neoplasms. In this review, we have focused on emphasizing recent achievements in virotherapy, both as a monotherapy and in combination with other therapeutic schemes to improve survival rate and quality of life among patients with glioblastoma.

Ageenko A. , Vasileva N. , Richter V. , Kuligina E.
Combination of Oncolytic Virotherapy with Different Antitumor Approaches against Glioblastoma
International Journal of Molecular Sciences. 2024. V.25. N4. 2042 . DOI: 10.3390/ijms25042042 WOS Scopus OpenAlex

Published print:

Mar 7, 2024

Web of science:	WOS:001170007300001
Scopus:	2-s2.0-85185910093
OpenAlex:	W4391598178

DB	Citing
OpenAlex	4
Web of science	3
Scopus	1