Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo

Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo Научная публикация

Журнал

International Journal of Molecular Sciences
, E-ISSN: 1422-0067

Вых. Данные

Год: 2022, Том: 23, Номер: 11, Номер статьи : 6214, Страниц : DOI: 10.3390/ijms23116214

Ключевые слова

18βH-glycyrrhetinic acid; ABC transporters; anti-inflammatory activity; anti-metastatic activity; apoptosis; CDDO-Me; epoxide; pharmacophore group; soloxolone methyl; toxicity

Авторы

Salomatina Oksana V. ^1,2 , Sen’kova Aleksandra V. ¹ , Moralev Arseny D. ^1,3 , Savin Innokenty A. ¹ , Komarova Nina I. ² , Salakhutdinov Nariman F. ² , Zenkova Marina A. ¹ , Markov Andrey V. ¹

Организации

1	Институт химической биологии и фундаментальной медицины СО РАН
2	Новосибирский институт органической химии им. Н.Н. Ворожцова СО РАН
3	Новосибирский государственный университет

Salomatina O.V. , Sen’kova A.V. , Moralev A.D. , Savin I.A. , Komarova N.I. , Salakhutdinov N.F. , Zenkova M.A. , Markov A.V.
Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo
International Journal of Molecular Sciences. 2022. Т.23. №11. 6214 . DOI: 10.3390/ijms23116214 WOS Scopus OpenAlex

Опубликована в печати:

1 июн. 2022 г.

Web of science:	WOS:000808861300001
Scopus:	2-s2.0-85131703860
OpenAlex:	W4281810586

БД	Цитирований
Scopus	4
OpenAlex	11
Web of science	10