Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo

Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo Full article

Journal

International Journal of Molecular Sciences
, E-ISSN: 1422-0067

Output data

Year: 2022, Volume: 23, Number: 11, Article number : 6214, Pages count : DOI: 10.3390/ijms23116214

Tags

18βH-glycyrrhetinic acid; ABC transporters; anti-inflammatory activity; anti-metastatic activity; apoptosis; CDDO-Me; epoxide; pharmacophore group; soloxolone methyl; toxicity

Authors

Salomatina Oksana V. ^1,2 , Sen’kova Aleksandra V. ¹ , Moralev Arseny D. ^1,3 , Savin Innokenty A. ¹ , Komarova Nina I. ² , Salakhutdinov Nariman F. ² , Zenkova Marina A. ¹ , Markov Andrey V. ¹

Affiliations

1	Институт химической биологии и фундаментальной медицины СО РАН
2	Новосибирский институт органической химии им. Н.Н. Ворожцова СО РАН
3	Новосибирский государственный университет

Salomatina O.V. , Sen’kova A.V. , Moralev A.D. , Savin I.A. , Komarova N.I. , Salakhutdinov N.F. , Zenkova M.A. , Markov A.V.
Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo
International Journal of Molecular Sciences. 2022. Т.23. №11. 6214 . DOI: 10.3390/ijms23116214 WOS Scopus OpenAlex

Published print:

Jun 1, 2022

Web of science:	WOS:000808861300001
Scopus:	2-s2.0-85131703860
OpenAlex:	W4281810586

DB	Citing
Scopus	4
OpenAlex	11
Web of science	10