Acute gastroenteritis with a new coronavirus infection in novosibirsk residents [Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска]

Acute gastroenteritis with a new coronavirus infection in novosibirsk residents [Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска] Научная публикация

Журнал

Экспериментальная и клиническая гастроэнтерология (Experimental and Clinical Gastroenterology, Eksperimental'naya i Klinicheskaya Gastroenterologiya)
ISSN: 1682-8658

Вых. Данные

Год: 2021, Номер: 6, Страницы: 12-17 Страниц : 6 DOI: 10.31146/1682-8658-ECG-190-6-12-17

Ключевые слова

Acute gastroenteritis; Covid-19; Gastrointestinal syndrome; New coronavirus infection; Polymerase chain reaction; Sars-cov-2

Авторы

Krasnova E.I. ¹ , Provorova V.V. ¹ , Khokhlova N.I. ¹ , Borodina E.V. ¹ , Sheronova O.B. ² , Tikunova N.V. ³ , Kuznetsova V.G. ¹ , Kuimova I.V. ¹ , Izvekova I.Ya. ¹ , Panasenko L.M. ¹ , Pomogaeva A.P. ⁴ , Lukashova L.V. ⁴ , Evstropov A.N. ¹

Организации

1	Novosibirsk State Medical University of Ministry of Health of Russian Federation, Krasniy prospekt, 52, Novosibirsk, 630091, Russian Federation
2	City Infectious Diseases Clinical Hospital No. 1, Novosibirsk, 630099, Russian Federation
3	Fgbun Institute of Chemical Biology and Fundamental Medicine Sb Ras, Novosibirsk, 630090, Russian Federation
4	Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russian Federation

The aim of the study was to determine the frequency and clinical and laboratory features of acute gastroenteritis (OGE) in adult residents of Novosibirsk hospitalized with a new coronavirus infection (COVID-19) in 2020. Materials and methods. We examined 3581 patients aged 18 to 96 years with a diagnosis of New coronavirus infection, confi rmed by the detection of SARS-CoV-2 RNA in the mucus from the oropharynx by PCR, hospitalized in the State Medical Institution NSO GICB No. 1 in 2020. Along with the generally accepted diagnostic methods, feces were examined by PCR in 50 patients with gastrointestinal syndrome to detect SARS-CoV-2 RNA using a set of original specifi c primers. Results. Of the 3,581 hospitalized adult patients with COVID-19, 74% of cases were diagnosed with bilateral polysegmental pneumonia, and 26% of cases were diagnosed with acute respiratory infection. Manifestations of OGE were observed in 6.8% (n=243) of patients. In the group of 50 COVID-19 patients, in whom the disease began with symptoms of OGE, it came to the fore in the clinical picture of the disease in 20% of cases, and SARS-Co- V2 RNA in the feces was detected in 62% of patients. Conclusion The established frequency of OGE in COVID-19 in adults shows the need to develop and implement in clinical practice test systems (PCR of SARS-CoV-2 RNA in feces) for the diagnosis of the intestinal form of a new coronavirus infection. © 2021 Eksperimental'naya i Klinicheskaya Gastroenterologiya. All rights reserved.

Krasnova E.I. , Provorova V.V. , Khokhlova N.I. , Borodina E.V. , Sheronova O.B. , Tikunova N.V. , Kuznetsova V.G. , Kuimova I.V. , Izvekova I.Y. , Panasenko L.M. , Pomogaeva A.P. , Lukashova L.V. , Evstropov A.N.
Acute gastroenteritis with a new coronavirus infection in novosibirsk residents [Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска]
Экспериментальная и клиническая гастроэнтерология (Experimental and Clinical Gastroenterology, Eksperimental'naya i Klinicheskaya Gastroenterologiya). 2021. N6. P.12-17. DOI: 10.31146/1682-8658-ECG-190-6-12-17 Scopus OpenAlex

Краснова Е.И. , Проворова В.В. , Хохлова Н.И. , Майбородина Е.В. , Шеронова О.Б. , Тикунова Н.В. , Кузнецова В.Г. , Куимова И.В. , Извекова И.Я. , Панасенко Л.М. , Помогаева А.П. , Лукашова Л.В. , Евстропов А.Н.
Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска
Экспериментальная и клиническая гастроэнтерология (Experimental and Clinical Gastroenterology, Eksperimental'naya i Klinicheskaya Gastroenterologiya). 2021. №6 (190). С.12-17. РИНЦ

Scopus:	2-s2.0-85115320799
OpenAlex:	W3197255591

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