Abstract: The aim of the study was to determine the frequency and clinical and laboratory features of acute gastroenteritis (OGE) in adult residents of Novosibirsk hospitalized with a new coronavirus infection (COVID-19) in 2020. Materials and methods. We examined 3581 patients aged 18 to 96 years with a diagnosis of New coronavirus infection, confi rmed by the detection of SARS-CoV-2 RNA in the mucus from the oropharynx by PCR, hospitalized in the State Medical Institution NSO GICB No. 1 in 2020. Along with the generally accepted diagnostic methods, feces were examined by PCR in 50 patients with gastrointestinal syndrome to detect SARS-CoV-2 RNA using a set of original specifi c primers. Results. Of the 3,581 hospitalized adult patients with COVID-19, 74% of cases were diagnosed with bilateral polysegmental pneumonia, and 26% of cases were diagnosed with acute respiratory infection. Manifestations of OGE were observed in 6.8% (n=243) of patients. In the group of 50 COVID-19 patients, in whom the disease began with symptoms of OGE, it came to the fore in the clinical picture of the disease in 20% of cases, and SARS-Co- V2 RNA in the feces was detected in 62% of patients. Conclusion The established frequency of OGE in COVID-19 in adults shows the need to develop and implement in clinical practice test systems (PCR of SARS-CoV-2 RNA in feces) for the diagnosis of the intestinal form of a new coronavirus infection. © 2021 Eksperimental'naya i Klinicheskaya Gastroenterologiya. All rights reserved.

Cite: Krasnova E.I. , Provorova V.V. , Khokhlova N.I. , Borodina E.V. , Sheronova O.B. , Tikunova N.V. , Kuznetsova V.G. , Kuimova I.V. , Izvekova I.Y. , Panasenko L.M. , Pomogaeva A.P. , Lukashova L.V. , Evstropov A.N.
Acute gastroenteritis with a new coronavirus infection in novosibirsk residents [Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска]
Экспериментальная и клиническая гастроэнтерология (Experimental and Clinical Gastroenterology, Eksperimental'naya i Klinicheskaya Gastroenterologiya). 2021. N6. P.12-17. DOI: 10.31146/1682-8658-ECG-190-6-12-17 Scopus OpenAlex

Original: Краснова Е.И. , Проворова В.В. , Хохлова Н.И. , Майбородина Е.В. , Шеронова О.Б. , Тикунова Н.В. , Кузнецова В.Г. , Куимова И.В. , Извекова И.Я. , Панасенко Л.М. , Помогаева А.П. , Лукашова Л.В. , Евстропов А.Н.
Острый гастроэнтерит при новой коронавирусной инфекции у жителей Новосибирска
Экспериментальная и клиническая гастроэнтерология (Experimental and Clinical Gastroenterology, Eksperimental'naya i Klinicheskaya Gastroenterologiya). 2021. №6 (190). С.12-17. РИНЦ

Identifiers:

Scopus:	2-s2.0-85115320799
OpenAlex:	W3197255591

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